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本文通过鼠伤寒沙门氏菌致突变试验（ Ａｍｅｓ Ｔｅｓｔ） ，分析常用氯化消毒方法对饮用水遗传毒性的影响。水样采自某单位自备水源。试验结果表明，未氯化自来水有机提取物致突变反应阴性，加氯自来水样诱发沙门氏菌致突变率升高；在一定范围内，随氯浓度增加，不会显著增加水样的致突变性。同时检测加氯后中和水样的致突变性，加中和剂处理后水样致突变性降低。提示加氯消毒水样致突变性可以通过水处理工艺加以改进，为饮水氯化消毒的致突变研究及其防治提供毒理学依据。
In this paper, Salmonella typhimurium mutagenicity test (Ames Test), analysis of chlorinated disinfection methods commonly used in drinking water genetic toxicity. Water samples taken from a unit of own water. The results showed that the mutagenicity of the organic extract of unchlorinated tap water was negative, and the mutagenicity of salmonella induced by chlorinated tap water was increased. In a certain range, the mutagenicity of water samples did not increase significantly with the increase of chlorine concentration. At the same time, the mutagenicity of neutralized water samples after chlorination was tested, and the mutagenicity of water samples treated with neutralizer was reduced. It is suggested that the mutagenicity of chlorinated disinfection water samples can be improved by water treatment process, providing toxicological basis for the mutagenesis and prevention of drinking water chlorination.