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目的:观察中西医结合治疗桥本甲状腺炎的临床疗效。方法:选取66例桥本甲状腺炎患者66例,按随机数字表法,将其分为两组,治疗组33例与对照组33例,对照组给予西药优甲乐进行治疗;治疗组在对照组治疗基础之上,采用消瘿汤治疗,然后对两组患者的临床疗效进行观察和比较。结果:经治疗后,治疗组的总有效率(90.9%)明显高于对照组(69.7%),差异有统计学意义(P<0.05);治疗后,治疗组与对照组患者的TGAb、TPOAb等指标均低于本组治疗前,差异有统计学意义(P<0.05);治疗组治疗后的TGAb、TPOAb等指标与对照组相比较,差异有统计学意义(P<0.05);治疗组与对照组治疗后的FT3、FT4均高于本组治疗前,而治疗后的TSH指标低于本组治疗前,差异有统计学意义(P<0.05);治疗组治疗后的FT3、FT4均高于对照组,且其TSH指标低于对照组,两组比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗桥本甲状腺炎疗效显著,且可有效改善患者的自身免疫状态。
Objective: To observe the clinical curative effect of Hashimoto’s thyroiditis treated with integrated traditional Chinese and western medicine. Methods: Sixty-six patients with Hashimoto’s thyroiditis were selected. Sixty-six patients with Hashimoto’s thyroiditis were divided into two groups according to the random number table method. 33 cases in the treatment group and 33 cases in the control group were treated with Euthyrox, On the basis of group therapy, Xiaoyu Decoction was used for treatment, and then the clinical efficacy of the two groups were observed and compared. Results: After treatment, the total effective rate (90.9%) in the treatment group was significantly higher than that in the control group (69.7%), the difference was statistically significant (P <0.05); After treatment, the TGAb, TPOAb (P <0.05). The indexes of TGAb and TPOAb after treatment in the treatment group were significantly different from those in the control group (P <0.05). The treatment group Compared with the control group before and after treatment, the FT3 and FT4 levels in the treatment group were significantly higher than those before treatment, while the TSH level after treatment was lower than that in the control group before treatment (P <0.05). FT3 and FT4 in the treatment group Higher than the control group, and the TSH index was lower than the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion: Integrative treatment of Hashimoto’s thyroiditis has a significant effect, and can effectively improve the patient’s autoimmune state.