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目的：采用高频彩色多普勒超声实时引导锁骨下静脉精确置管对导管相关性血流感染发生率影响的临床研究，降低导管血流感染发生率。方法将实施锁骨下静脉精确置管的48例患者随机分为观察组和对照组，每组各24例，其中观察组采用高频彩色多普勒超声显像进行锁骨下静脉精确置管；而对照组则采用常规的方法进行置管，对所得的相关数据均采用SPSS13．0软件进行分析处理。结果两组患者临床资料比较差异无统计学意义；观察组锁骨下静脉精确置管一次成功23例占95．83％，对照组一次成功18例占75．00％；置管操作时间＜2 min者观察组21例、对照组9例；出现并发症观察组2例占8．33％、对照组7例占29．17％；置管一段时间后进行血液细菌检查，结果显示观察组感染1例占4．17％、对照组感染3例占12．50％；4个指标观察组与对照组对比差异均有统计学意义（P＜0．05）。结论采用高频彩色多普勒超声引导锁骨下静脉精确置管和常规置管相比操作简便安全、异常成功率较高、并发症和感染率比较低，在临床上对于锁骨下静脉精确置管有一定的临床指导意义。“,”OBJECTIVE To discuss the influence of real‐time high‐frequency color Doppler ultrasound guided subclavian vein catheterization on catheter‐related bloodstream infection so as to reduce the incidence of catheter bloodstream infections .METHODS Totally 48 patients undergoing subclavian vein catheterization were randomly divided into the observation group and the control group ,24 cases in each group .The observation group used high‐frequency color Doppler ultrasound imaging for precise subclavian vein catheterization , while the control group used the conventional method for catheterization .Data were processed by the software SPSS 13 .0 .RESULTS The difference in general information between the two groups was notsignificant .The one‐time successful rate for precise catheterization was 95 .83% (23 cases) in the observation group and 75 .00% (18 cases) in the control group .Totally 21 cases in the observation group and 9 cases in the test group had tube operating time < 2 minutes .Complications occurred in 2 cases in the observation group (8 .33% ) and 7 cases in the control group (29 .17% ) .The blood bacteriological examination in a period after catheterization showed one case of infection (4 .17% ) in the observation group and three cases of infections (12 .50% ) in the control group . There was significant difference in the four indicators between the observation group and the control group (P< 0 .05) . CONCLUSION Compared to the conventional method ,the high frequency color Doppler ultrasound‐guided precise supraclavicular vein catheterization is safer and more convenient with higher successful rate and lower complications and infection rates , which has certain clinical significance for precise supraclavicular vein catheterization .