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目的:探讨宫颈微偏腺癌的临床病理特征、诊断和治疗。方法:对7例宫颈微偏腺癌的临床病理资料进行分析。结果:7例患者的平均年龄为46.5岁,临床症状以大量阴道流液为主,体征多表现为宫颈肥大、宫颈管变硬;术前病理确诊2例,可疑3例;手术加放疗、化疗4例,手术加放疗3例。结论:宫颈微偏腺癌的早期确诊率低,临床应高度警惕阴道大量流液和/或宫颈肥大者,争取宫颈深部活检或宫颈管搔刮,必要时行宫颈锥切术。CEA、CK、P53、K i-67(+),而ER、PR(-)具有辅助诊断价值。
Objective: To investigate the clinicopathological features, diagnosis and treatment of cervical micro-adenocarcinoma. Methods: Clinical and pathological data of 7 cases of cervical micro-adenocarcinoma were analyzed. Results: The average age of 7 patients was 46.5 years old. The clinical symptoms were mainly vaginal fluid. The symptoms were mostly cervical hypertrophy and cervical canal hardening. Preoperative pathology was diagnosed in 2 cases and suspicious in 3 cases. The surgery plus radiotherapy and chemotherapy 4 cases, surgery and radiotherapy in 3 cases. Conclusion: The early diagnosis of cervical micro-adenocarcinoma of the low rate of clinical should be highly vigilant vaginal fluid and / or cervical hypertrophy for cervical deep biopsy or cervical scraping, cervical conization if necessary. CEA, CK, P53, K i-67 (+), while ER, PR (-) have diagnostic value.