Targeting cell death signaling in colorectal cancer:Current strategies and future perspectives

• 作 者: Bruno Christian Koehler Dirk J
• 机 构: NationalCenterforTumorDiseasesUniversityHospitalsHeidelberg69120HeidelbergGermany
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2014年8期
• 关键词: COLORECTAL cancer Apoptosis NECROPTOSIS AUTOPHAGY Colorectal cancer Apoptosis
• 基金项目: BCK holds a Postdoctoral-Fellowship from the Medical Faculty of the University of Heidelberg,Germany,HSB receives grants from the German Research Foundation (DFG SCHU 1443/4-1)

The evasion from controlled cell death induction has been considered as one of the hallmarks of cancer cells.Defects in cell death signaling are a fundamental phenomenon in colorectal cancer.Nearly any non-invasive cancer treatment finally aims to induce