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利奈唑胺是第一个应用于临床的新型噁唑烷酮类抗生素,对革兰氏阳性菌的抗菌谱广,近年来国内有文献报道,本品可致血小板减少,现概述如下。张月莉报道,患女,88岁,因葡萄球菌感染给予利奈唑胺300 mg静滴,bid,用药前血小板90×109/L,用药第14天,血小板降至54×109/L,即停药,予对症治疗,7天后复查血小板129×109/L。[1]周叶报道,患女,62岁,因腹腔感染给予利奈唑胺600 mg静滴,q12 h,用药前血小板142×109/L,
Linezolid is the first new clinical application of oxazolidinone antibiotics, antibacterial spectrum of Gram-positive bacteria is widely reported in the literature in recent years, this product can cause thrombocytopenia, are summarized as follows. Zhang Yueli reported that suffering from women, 88 years old, due to staphylococcal infection with linezolid 300 mg bid, pretreatment platelets 90 × 109 / L, 14 days of treatment, platelets down to 54 × 109 / L, that is, withdrawal , To symptomatic treatment, review of platelets after 7 days 129 × 109 / L. [1] reported in Zhou Ye, suffering from women, aged 62, was given intraperitoneal linezolid 600 mg intravenous infusion, q12 h, 142 × 109 / L before administration of platelets,