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由于涎腺基底细胞腺瘤和腺癌在形态学方面表现相似,其主要区别在于肿瘤是否浸润生长至涎腺实质和(或)涎腺外组织,因而涎腺基底细胞肿瘤的鉴别诊断存在挑战,尤其对于穿刺活检标本。CTNNB1基因位于染色体3p21,β-catenin是其编码产物蛋白。Jo等检测73例涎腺肿瘤(22例基底细胞腺瘤、3例基底细胞腺癌、20例多形性腺瘤、20例腺
Because salivary basal cell adenocarcinoma and adenocarcinoma resemble morphologically, the main difference is whether the tumor infiltrates the salivary gland parenchyma and / or salivary gland tissue. Therefore, the differential diagnosis of salivary basal cell carcinoma presents challenges. Especially for biopsy specimens. The CTNNB1 gene is located on chromosome 3p21 and the β-catenin is its encoded product protein. Jo detected 73 cases of salivary gland tumors (22 cases of basal cell adenoma, 3 cases of basal adenocarcinoma, 20 cases of pleomorphic adenoma, 20 cases of adenoma