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【目的】探讨产科弥漫性血管内凝血（DIC）患者救治前后 D-二聚体（DD）、纤维蛋白原（FIB）、部分凝血酶活时间（APTT）、血小板计数（PLT）水平的变化及意义。【方法】选择本院2009年1月至2012年8月收治的28例DIC产妇为观察对象，在患者DIC发生前后及至救治成功进行动态DD、FIB、APTT、PLT（每6 h一次，病情稳定后每天1～2次）的测定，观察治疗前后的测定结果。【结果】28例产妇发生DIC时，DD明显上升，FIB减少，APTT 时间延长，血小板进行性下降，治疗后各指标明显改善，两阶段比较差异明显（P ＜0．05）。28例患者经救治后均康复出院。【结论】对产科DIC患者动态检测DD、FIB、APTT、PLT有助于临床诊断和监测患者预后。“,”[Obj ective]To explore the changes of D-dimer(DD),fibrinogen(FIB),activated partial throm-boplastin time(APTT)and platelet(PLT)of patients with disseminated intravascular coagulation(DIC)in ob-stetric department before and after treatment and the significance.[Methods]A total of 28 DIC parturients in our hospital from Jan.2009 to Aug.2012 were selected as the observation subjects.Dynamic DD,FIB, APTT and PLT before and after the occurrence of DIC and until successful treatment were measured(once per 6h and 1~2 times every day after stable condition).The measurement result before and after treatment was observed.[Results]The DD of 28 parturients with DIC was obviously increased,and FIB was decreased,and APTT was prolonged,and PLT was reduced progressively.All indexes after treatment were improved,and there was significant difference between two stages(P<0.05).All 28 patients were recovered and discharged after treatment.[Conclusion]Dynamic detection of DD,FIB,APTT and PLT is helpful for clinical diagnosis and the monitoring of the prognosis of patients.