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作者对60例经临床和超声显像证实为胆石症伴胆绞痛的患者,进行了前列腺素抑制剂止痛效果的研究。 全部病人随机分为三组,均在急诊室观察24小时。对有腹膜刺激症,特别是右上腹有明显肌卫及反跳痛;或肛温超过37.5℃,白血球超过10000/mm~3,血清及尿分析超过正常值;或有消化性溃疡病史,对双氯灭痛过敏者均不列入研究。第一组20人,使用安慰剂生理盐水3ml肌肉注射,平均年龄61岁。第二组20人,使用罂粟碱80mg肌肉注射,平均年龄58岁。第三组20人,使用双氯灭痛75mg肌肉注射,平均年龄65岁。为了对照分析双氯灭痛的止痛效果,对20例轻微背疼的患者也进行了观察。
The authors of 60 patients confirmed by clinical and ultrasound imaging of cholelithiasis with biliary colic in patients with prostaglandin inhibitor analgesic effect. All patients were randomly divided into three groups, were observed in the emergency room for 24 hours. For peritoneal irritation, especially the right upper quadrant has obvious myopathy and rebound tenderness; or rectal temperature over 37.5 ℃, white blood cells over 10000 / mm ~ 3, serum and urine analysis of more than normal; or a history of peptic ulcer, Diclofenac allergy were not included in the study. The first group of 20 people, using placebo saline 3ml intramuscular injection, mean age 61 years old. The second group of 20 people, using papaverine 80mg intramuscular injection, mean age 58 years old. The third group of 20 people, the use of diclofenac 75mg intramuscular injection, with an average age of 65 years. In order to analyze the analgesic effect of diclofenac, 20 patients with mild back pain were also observed.