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目的探讨原发性十二指肠恶性肿瘤诊断方法及手术治疗效果。方法对50例原发性十二指肠恶性肿瘤患者的临床资料进行分析。结果本组患者经上消化道造影、十二指肠镜、CT检查确诊率分别是86%、85%和67%。根治性胰十二指肠切除术28例,术后1、2、5年生存率分别为77%、70%和32%。十二指肠乳头局部切除术4例,分别于术后8～10个月复发死亡。节段性十二指肠切除的6例,术后最长存活19个月。姑息性手术或无法手术者12例,均于术后1～7个月死亡。结论十二指肠镜检查对十二指肠恶性肿瘤确诊率高;根治性胰十二指肠切除术可提高患者的5年生存率。
Objective To investigate the diagnosis and surgical treatment of primary duodenal malignancies. Methods The clinical data of 50 patients with primary duodenal malignant tumor were analyzed. The results of this group of patients by upper gastrointestinal imaging, duodenoscopy, CT examination confirmed rates were 86%, 85% and 67%. In the 28 cases of radical pancreatoduodenectomy, the survival rates at one, two and five years after surgery were 77%, 70% and 32% respectively. Four cases of partial duodenal papilla resection, respectively, 8 to 10 months after the recurrence of death. Six cases of segmental duodenal resection, the longest survival after 19 months. Palliative surgery or surgery in 12 cases, were 1 to 7 months after the death. Conclusions Duodenoscopy has a high diagnosis rate of duodenal malignancies. Radical pancreatoduodenectomy can improve the 5-year survival rate of patients.