超敏C反应蛋白联合肺炎支原体抗体测定在儿童支原体肺炎中的临床应用价值

• 作 者: 杨胜高
• 机 构: 贵州省余庆县人民医院检验科,贵州 遵义 564499
• 出 处: 健康必读
• 发表日期: 2022年3期
• 关键词: Mycoplasma pneumonia Mycoplasma pneumoniae antibody Hypersensitive C-reactive pr

目的:评价超敏C反应蛋白(hs-CRP)与肺炎支原体抗体(MP-Ab)联合检测对于支原体肺炎(MP)患儿感染的诊断价值.方法:选取2018年至2020年在我院治疗的152例MP患儿作为实验组,选取同期在我院体检的152例健康儿童作为对照组.比较实验组与对照组儿童hs-CRP与MP-Ab滴度,比较两组患儿hs-CRP、MP-Ab诊断MP的阳性率,比较两组患儿hs-CRP、MP-Ab及二者联合诊断MP的灵敏度、特异度.结果:实验组≥1:40与≥1:80的MP-Ab滴度患儿比例与hs-CRP较对照组显著提高(均“,”Objective: To evaluate the diagnostic value of combined detection of high-sensitivity C-reactive protein (hs-CRP) and Mycoplasma pneumoniae antibody (MP-Ab) for mycoplasma pneumonia (MP) infection in children. Methods152 children with MP who were treated in our hospital from 2018 to 2020 were selected as the experimental group, and 152 healthy children who received physical examination in our hospital during the same period were selected as the control group. Compare the titers of hs-CRP and MP-Ab in the experimental group and the control group, compare the positive rates of hs-CRP and MP-Ab in the diagnosis of MP in the two groups, compare hs-CRP, MP-Ab and the two in the two groups The sensitivity and specificity of combined diagnosis of MP. Results The proportion of children with MP-Ab titers ≥1:40 and ≥1:80 in the experimental group and hs-CRP were significantly higher than those in the control group (both P ＜ 0.001), and the positive rate of hs-CRP and MP-Ab in the experimental group Significantly higher than the control group (all P ＜ 0.001). The sensitivity and specificity of combined hs-CRP and MP-Ab in the diagnosis of MP children were 89.3％ and 89.6％, which were significantly higher than that of hs-CRP and MP-Ab alone. Conclusion The combination of hs-CRP and MP-Ab has high sensitivity and specificity in the diagnosis of children with mycoplasma pneumonia, and it is worthy of clinical promotion.