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目的 探讨米索前列醇预防和治疗产后出血的临床效果。方法 对 2 0 0 1年 7月～ 2 0 0 2年 8月在我院产科住院的足月妊娠顺产的产妇 1 96例 ,随机分成米索前列醇组 (米索组 )、催产素组、对照组 ,对三组产后 2小时出血量进行比较。结果 米索组产后 2小时出血量明显低于催产素组和对照组 (P<0 .0 5、 P<0 .0 1 ) ,且米索前列醇直肠给药无明显胃肠道反应。结论 米索前列醇在预防、减少和治疗产后出血 ,降低孕产妇死亡率 ,减少输血用量等方面 ,具有临床使用价值
Objective To investigate the clinical effect of misoprostol in preventing and treating postpartum hemorrhage. Methods One hundred and sixty-six cases of full-term pregnant women who were hospitalized in obstetrics department of our hospital from July 2001 to August 2002 were randomly divided into misoprostol group (misoprostol group), oxytocin group, The control group, three groups of postpartum 2 hours of bleeding were compared. Results The bleeding volume of misoprostol 2 hours postpartum was significantly lower than that of oxytocin and control group (P <0.05, P <0.01), and there was no significant gastrointestinal reaction of misoprostol rectally. Conclusion Misoprostol has clinical value in preventing, reducing and treating postpartum hemorrhage, reducing maternal mortality and reducing transfusion dosage