论文部分内容阅读
我们对进入海拔3600米的东部帕米尔高原后发生急性高山病的74例患者进行免疫状态的研究。发现急性高山病患者伴有T淋巴细胞、B淋巴细胞和A—免疫部分指数障碍,这一现象约持续5个月。急性高山病细胞免疫紊乱表现为T淋巴细胞减少和减弱在PHA和ConA影响下的T淋巴未成熟细胞的变形能力,同时减少T辅助细胞和增加T抑制细胞水平。急性高山病伴有血液B淋巴细胞绝对数减少但并不影响有效抗体的产生。同时发现和适应良好的受试者比出现大量的功能不全的单核细胞。在急性高山病发病过程中出现的单核细胞功能的减退表现为单核细胞
We studied the immune status of 74 patients with acute mountain sickness after entering the Pamir plateau at an altitude of 3,600 meters. Found in patients with acute mountain sickness with T lymphocytes, B lymphocytes and A-immune index disorder, this phenomenon lasted about 5 months. Acute mountain sickness Immune disorders are manifested by T-lymphocyte depletion and attenuation of the deformability of T-lymphocyte immature cells under the influence of PHA and ConA, while reducing T-helper cells and increasing T-suppressor cell levels. The absolute number of acute mountain sickness with blood B lymphocytes decreases but does not affect the production of effective antibodies. At the same time, a large number of dysfunctional monocytes were found in well-adapted subjects. The decline of monocyte function during the onset of acute mountain sickness appears as monocytic