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目的观察马来酸曲美布汀治疗肠易激综合征的临床疗效。方法将156例治疗肠易激综合征患者随机分成治疗组和对照组,治疗组给予马来酸曲美布汀胶囊200 mg,3次/d,餐前温开水吞服;对照组给予胃复安10 mg口服,3次/d,两组疗程均为4周。结果治疗组总有效率为88.46%,与对照组相比差异有统计学意义(P<0.05)。结论马来酸曲美布汀治疗肠易激综合征安全性好,不良反应发生率较低,值得临床推广应用。
Objective To observe the clinical efficacy of trimebutine maleate in the treatment of irritable bowel syndrome. Methods 156 cases of irritable bowel syndrome patients were randomly divided into treatment group and control group, the treatment group were given trimebutine maleate capsules 200 mg, 3 times / d, warm water swallow before meals; the control group given stomach complex An 10 mg orally, 3 times / d, two courses of treatment were 4 weeks. Results The total effective rate in the treatment group was 88.46%, which was significantly different from that in the control group (P <0.05). Conclusion trimebutine maleate treatment of irritable bowel syndrome is safe, the incidence of adverse reactions is low, worthy of clinical application.