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多年来,各地用氯(合)霉素治疗伤寒、副伤寒取得较好疗效。但是,由于药物的副作用,不少病例发生了白细胞计数降低和粒细胞减少;另外,由于耐氯霉素菌株的产生,一些病例被迫更换药物,因此,有必要选用新的有效抗菌药物。我科用复方新诺明[磺胺甲基异(口恶)唑(SMZ)+甲氧苄氨嘧啶(TMP)]治疗伤寒、副伤寒120例,并和用氯霉素治疗的50例作了比较,结果报告如下。一、一般临床资料1.病例来源及治疗分组本文系统观察自1973年12月至1975年12月底确诊的170例(伤寒
Over the years, all over with chlorine (co) mold for typhoid fever, paratyphoid get better effect. However, due to side effects of drugs, leukopenia and neutropenia have occurred in many cases. In addition, some new cases of effective antimicrobial agents are necessary because some chloramphenicol-resistant strains are forced to change drugs. In our department, 120 cases of typhoid and paratyphoid were treated with the combination of sulfamethoxazole (SMZ) and trimethoprim (TMP), and 50 cases were treated with chloramphenicol The results are reported below. First, the general clinical data 1. The source of the cases and treatment group This article systematically observed from December 1973 to the end of December 1975 confirmed 170 cases (typhoid fever