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[目的]探讨恶性肿瘤患者贫血的发生情况及其相关危险因素。[方法]回顾性分析我院综合科2010年1月至12月收治的986例恶性肿瘤患者,进行单因素和多因素Logistic回归分析。[结果]所有患者中,男性573例(58.2%),女性413例(41.8%),死亡124例,贫血669例,贫血发生率为67.8%。Ⅰ级295例(44.1%),Ⅱ级218例(32.6%),Ⅲ级87例(13.0%),Ⅳ级69例(10.3%)。胃肠道肿瘤贫血发生率最高为77.5%。单因素分析显示,年龄、肿瘤分期、抗肿瘤治疗、肿瘤类型、合并出血与恶性肿瘤贫血的发生有关,具有统计学意义(P<0.05)。多因素Logistic回归分析显示,合并出血、临床分期、抗肿瘤治疗与贫血发生密切相关。[结论]恶性肿瘤患者贫血发生率较高;肿瘤分期、合并出血和抗肿瘤治疗是恶性肿瘤贫血发生的危险因素。
[Objective] To investigate the occurrence and related risk factors of anemia in patients with malignant tumors. [Methods] A retrospective analysis of 986 cases of malignant tumor admitted to General Hospital of our hospital from January to December 2010 was conducted by univariate and multivariate Logistic regression analysis. [Results] Among all the patients, 573 (58.2%) were male and 413 (41.8%) were female, 124 died, 669 anemia and 67.8% anemia. Grade I 295 (44.1%), Grade II 218 (32.6%), Grade III 87 (13.0%), Grade IV 69 (10.3%). The highest incidence of gastrointestinal cancer anemia was 77.5%. Univariate analysis showed that age, tumor staging, anti-tumor therapy, tumor type, combined hemorrhage and malignant tumor anemia, with statistical significance (P <0.05). Multivariate Logistic regression analysis showed that combined bleeding, clinical stage, anti-tumor therapy and anemia are closely related. [Conclusion] The incidence of anemia in patients with malignant tumors is high. The staging, combined hemorrhage and anti-tumor therapy are the risk factors of anemia.