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对96例不稳定型心绞痛患者,采用常规治疗40例(对照组),加用尿激酶、阿斯匹林及潘生丁治疗56例(治疗组)。临床对照观察结果:住院期间胸痛平均缓解和消失时间治疗组明显效对照组短(P<0.01);ECG改善情况两组无明显差异(P>0.05);对照组发生急性心肌梗塞(AMI)2例、治疗组发生轻度出血4例。随访结果:近期、远期心绞痛复发率及近期AMI发生率对照组均高于治疗组(P<0.01);远期AMI发生率和死亡率两组间无显著差异(P>0.05)。
Forty-six patients with unstable angina pectoris were treated with conventional therapy (control group), plus urokinase, aspirin and dipyridamole in 56 cases (treatment group). The results of clinical observation: The average relief and disappearance time of chest pain during hospitalization were significantly shorter in the treatment group than in the control group (P <0.01); there was no significant difference between the two groups in ECG improvement (P> 0.05); acute myocardial infarction (AMI) in 2 cases, mild bleeding in the treatment group occurred in 4 cases. The follow-up results: Recently, the recurrence rate of long-term angina and recent incidence of AMI in the control group were higher than those in the treatment group (P <0.01). There was no significant difference in long-term AMI incidence and mortality between the two groups (P> 0.05 ).