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目的探讨干姜醋酸乙酯提取物的抗心律失常作用。方法分别用氯仿,乌头碱,哇巴因三种药物制备三种心律失常模型,观察干姜醋酸乙酯提取物对心律失常的拮抗作用。结果干姜醋酸乙酯提取物可降低室颤发生率,提高引起室性早搏、心搏停止的药物用量。结论干姜醋酸乙酯提取物具有一定抗心律失常作用。
Objective To investigate the antiarrhythmic effects of ethyl acetate extract from dried ginger. Methods Three arrhythmia models were prepared with chloroform, aconitine and ouabain, respectively. The antagonistic effects of ethyl acetate extract of dried ginger on arrhythmia were observed. Results Ginger ethyl acetate extract can reduce the incidence of ventricular fibrillation and increase the amount of drugs that cause premature ventricular contractions and cardiac arrest. Conclusion The ethyl acetate extract of dried ginger has antiarrhythmic effect.