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对39例有明确围产期缺氧史的新生儿(重度窒息12例,HIE27例)的预后及影响因素进行了分析。35例存活小儿分别在其3,6,9,12个月进行了Gesell法智能发育水平测定。预后良好及基本正常占82.05％,预后不良17.95％。经多元逐步回归分析,孕周、出生体重、脑水肿、颅内出血严重程度与预后关系密切.进一步进行单因素分析发现,孕周<34周,出生体重<1500g,脑水肿持续4天以上,颅内出血Ⅲ～Ⅳ°时对预后威胁最大,可作为疾病早期估价预后的参考.对脑损伤小儿进行早期干预,有助于挖掘发育潜力,在原有基础上改善预后。
The prognosis and influential factors of 39 neonates with severe hypoxia (12 cases of severe asphyxia and 27 cases of HIE) were analyzed. 35 cases of surviving children in their 3,6,9,12 months of Gesell method of intelligent development level. Good prognosis and basic normal accounted for 82.05%, poor prognosis 17.95%. By multiple stepwise regression analysis, gestational age, birth weight, cerebral edema, intracranial hemorrhage severity and prognosis are closely related.Further univariate analysis found that gestational age <34 weeks, birth weight <1500g, brain edema for more than 4 days, Internal hemorrhage Ⅲ ~ Ⅳ ° when the greatest threat to prognosis, can be used as early prognosis of disease reference. Early intervention in children with brain injury, help to tap the development potential, based on the original to improve prognosis.