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目的 探讨脑垂体瘤对肺功能的影响。方法 病例选择为 2 0 0 1年 7月～ 2 0 0 2年 6月临床诊断为脑垂体瘤并拟行脑垂体瘤切除术的患者 98例 (男 4 2例 ,女 5 6例 ) ,平均年龄 4 8.5± 1.4岁。所有患者在手术前后进行肺功能检查。结果 98例脑垂体瘤患者术前FEV1异常率 6 0 % ,术后异常率 2 2 % ,正常对照组异常 19% ;FEV1/Vcmax %术前异常率 18% ,术后异常率 12 % ,正常对照组异常 13% ;MVV术前异常率 78% ,术后异常率2 4 % ,正常对照组异常 15 % ;PEF术前异常率 79% ,术后异常率 19% ,正常对照组异常率 15 %。结论 脑垂体瘤患者术前EFV1降低 ,FEV1/Vcmax正常 ,MVV ,PEF降低 ,说明有限制性通气障碍 ,FEV1术后恢复与正常对照组无显著性差异。
Objective To investigate the effect of pituitary tumor on pulmonary function. Methods A total of 98 patients (42 males and 56 females) with clinical diagnosis of pituitary adenoma and pituitary adenoma resection from July 2001 to June 2002 were included in the study. The mean Age 4 8.5 ± 1.4 years old. All patients underwent lung function tests before and after surgery. Results 98 cases of pituitary adenoma preoperative FEV1 anomaly rate of 60%, postoperative anomalous rate of 22%, normal control group was abnormal 19%; FEV1 / Vcmax% preoperative 18%, postoperative anomalous rate of 12%, normal The control group was abnormal 13%; MVV preoperative 78%, postoperative 24%, normal 15%; PEF preoperative 79%, postoperative abnormal 19%, normal control 15 %. Conclusions Preoperative EFV1 decreased, FEV1 / Vcmax normal, MVV and PEF decreased in patients with pituitary adenoma, which indicated that there were no significant differences between the two groups.