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目的:观察格列美脲联合阿卡波糖治疗2型糖尿病的疗效。方法:112例2型糖尿病患者,随机分为两组。对照组56例,格列美脲片口服治疗;观察组56例,在对照组治疗的基础上给予阿卡波糖片50mg,3次/日,随第一口饭嚼服,均治疗3个月。结果:两组治疗后FPG、2hPG、HbA1C与治疗前组内相比较,两组均有明显下降(P<0.01);两组治疗后FPG组间比较,无显著差异(P>0.05);治疗后在2hPG、HbA1C两组组间比较,观察组明显优于对照组(P<0.05)。结论:格列美脲联合阿卡波糖治疗2型糖尿病疗效显著。
Objective: To observe the efficacy of glimepiride and acarbose in the treatment of type 2 diabetes mellitus. Methods: One hundred and twelve patients with type 2 diabetes were randomly divided into two groups. Control group of 56 patients, glimepiride tablets oral treatment; observation group of 56 patients in the control group based on the treatment of acarbose 50mg, 3 times / day, with the first meal chewing clothes, were treated 3 month. Results: The FPG, 2hPG and HbA1C after treatment in both groups were significantly decreased compared with those before treatment (P <0.01). There was no significant difference between the two groups in FPG after treatment (P> 0.05) After 2hPG, HbA1C comparison between the two groups, the observation group was significantly better than the control group (P <0.05). Conclusion: Glibenclamide combined with acarbose treatment of type 2 diabetes significant effect.