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[目的]分析子宫内膜透明细胞癌的临床特征、治疗方法和预后。[方法]回顾性分析1977年1月～2005年6月某院收治的子宫内膜透明细胞癌39例患者的病案资料、病理、治疗、随访情况。[结果]39例患者均采用手术治疗,1998年前17例患者行腔内放疗后行全子宫+双附件切除术,术后补充放疗;1998年以后22例患者行子宫内膜癌分期手术治疗,术后采取补充放疗或以化疗为主的综合治疗。化疗全部采用以铂类为主的方案。39例患者中,随访35例,随访时间最长30年,最短5个月。Ⅰ期5年生存率为80.81%。[结论]治疗采用以手术为主的综合治疗,术后尽早采用以铂类为主的方案化疗,对预防和治疗腹腔和远处转移有益。
[Objective] To analyze the clinical features, treatment and prognosis of endometrial clear cell carcinoma. [Methods] The medical records, pathology, treatment and follow-up of 39 cases of endometrial clear cell carcinoma admitted from January 1977 to June 2005 in our hospital were retrospectively analyzed. [Results] All the 39 patients were treated by surgery. In 1998, 17 patients underwent total hysterectomy and double-attachment resection after intra-cavity radiotherapy, and received radiotherapy after operation. Twenty-two patients underwent endoscopic surgical staging in 1998, Postoperative radiotherapy or chemotherapy-based comprehensive treatment. Chemotherapy using platinum-based programs. Among the 39 patients, 35 cases were followed up for a maximum of 30 years and the shortest was 5 months. Ⅰ-year 5-year survival rate was 80.81%. [Conclusion] The treatment is based on the comprehensive operation based on surgery. Platinum-based chemotherapy as soon as possible after operation is beneficial for the prevention and treatment of abdominal and distant metastasis.