{[K.18-Crown-6]Br_3}_n:保护胺和醇的三溴化催化剂(英文)

• 作 者: Gholamabbas Chehardoli Mohammad Ali Zolfigol Fateme Derakhshanpanah
• 机 构: Department of Medicinal Chemistry,School of Pharmacy,Hamedan University of Medical Sciences,Faculty
• 出 处: 催化学报
• 发表日期: 2013年09期
• 关键词: alcohols amines aromatic Crown crown utilized hexane diamine aldehydes guest

{[K.18-Crown-6]Br3}n , a unique tribromide-type catalyst, was utilized for the N-boc protection of amines and trimethylsilylation (TMS) and tetrahydropyranylation (THP) of alcohols. The method is general for the preparation of N-boc derivatives of aliphatic (acyclic and cyclic) and aromatic, and primary and secondary amines and also various TMS-ethers and THP-ethers. The simple separation of the catalyst from the product is one of the many advantages of this method.

{[K.18-Crown-6] Br3} n, a unique tribromide-type catalyst, was utilized for the N-boc protection of amines and trimethylsilylation (TMS) and tetrahydropyranylation (THP) of alcohols. The method is general for the preparation of N-boc derivatives of aliphatic (acyclic and cyclic) and aromatic, and primary and secondary amines and also various TMS-ethers and THP-ethers. The simple separation of the catalyst from the product is one of the many advantages of this method .