星形胶质细胞瘤的MRI与病理对照研究

• 作 者: 沈海林 丁乙 陈学仁 胡春洪 付引弟 康苏娅
• 机 构: 苏州医学院附属第一医院影像中心
• 出 处: 临床医学影像杂志
• 发表日期: 1998年02期
• 关键词: 星形胶质细胞瘤 MRI 病理对照研究 良性星形细胞瘤 分级诊断 磁共振成像 病理级别 瘤细胞 瘤血管 占位效应

目的：探讨星形胶质细胞瘤ＭＲＩ表现与病理分级之间的关系。材料方法：对４２例经病理证实幕上星形胶质细胞瘤的ＳＥＴ１ＷＩ、Ｔ２ＷＩ及Ｇｄ－ＤＴＰＡ增强图像与手术病理对照研究。结果：星形胶质细胞瘤的ＭＲＩ信号强度与病理分级有关。用ＭＲＩ评分标准，低级别星形细胞瘤均值为０４９±０２０，分化不良性星形细胞瘤为１２±０１７，多形性胶质母细胞瘤为１４７±０３４。经统计分析ＭＲＩ评分增加，病理级别亦增加（Ｐ＜００１－０００１）。结论：依靠ＭＲＩ信号差异可以达到病理分级诊断目的。星形胶质细胞瘤与瘤细胞多少、排列、变性及瘤血管多少相关

Objective: To investigate the relationship between MRI features and pathological grade of astrocytomas. Materials and Methods: A comparative study of SET1WI, T2WI and Gd-DTPA enhanced images and surgical pathology of 42 patients with supratentorial astrocytomas confirmed by pathology was performed. Results: The MRI signal intensity of astrocytoma is related to pathological grade. Using MRI scoring criteria, the mean value of low-grade astrocytomas was 049±020, poorly differentiated astrocytoma was 12±017, and pleomorphic glioblastoma was 147± 034. After statistical analysis of MRI scores increased, the pathological grade also increased (P <0  01-0  001). Conclusion: The difference in MRI signal can achieve the purpose of pathological grade diagnosis. Astroglioma is related to the number, arrangement, degeneration and tumor blood vessels of tumor cells