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苏州医学院血栓与止血研究室科研人员在阮长庚教授的带领下,首次研制成功了~(125)碘-6-酮前列腺素F_1 α放射免疫分析试剂盒,与此同时~(125)碘-血栓烷B_2放射免疫分析试剂盒亦获得成功。今年6月24日江苏省卫生厅组织省内外专家通过了鉴定。上述两种前列腺素的前体即血栓烷A_2(TXA_2)和前列环素(PGI_2)均具有强烈的生物活性,它们的平衡与失调,在止血和血栓形成中超重要作用,并且参与动脉粥样硬化、炎症、过敏与肿瘤转移等过程。它们极不稳定,很快自发性还原成稳定的无生物活性的
Under the leadership of Prof. Ruan Changgeng, researchers at the thrombosis and hemostasis laboratory of Suzhou Medical College successfully developed the 125I-6-keto prostaglandin F_1α radioimmunoassay kit for the first time, while the 125I- Thromboxane B 2 radioimmunoassay kit was also successful. June 24 this year, Jiangsu Provincial Health Department organized experts inside and outside the province passed the appraisal. Both prostaglandin precursors, thromboxane A 2 (TXA 2) and prostacyclin (PGI 2), have strong bioactivities, their balance and dysregulation play an important role in hemostasis and thrombosis and are involved in atherosclerosis , Inflammation, allergies and tumor metastasis process. They are extremely unstable and quickly spontaneously return to a stable, biologically inactive