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多器官功能衰竭(MOF)是临床治疗中出现的严重综合征,在颅脑疾病治疗过程中亦非少见。为了探讨颅脑疾病伴发MOP的诊断标准、发生机理、预后和治疗,本文总结分析了24个病例资料。结果表明,24个MOF病例中死亡率(19/24)高达79,2%,衰竭器官依次为肺、肾、肝、胃肠、脑、胰、心、血液系统,死亡率与受累器官数、年龄密切相关,而与GCS评分高低无关,并认为用脑疾病伴发MOF有其一定的独特性,尽管MOF目前预后极差,但及时正确的处理逆转各个受累器官是救治成功的关键。
Multiple organ failure (MOF) is a serious syndrome in clinical treatment, and is not uncommon in the treatment of craniocerebral diseases. In order to explore the diagnosis of brain disease associated with MOP criteria, the occurrence of the mechanism, prognosis and treatment, the paper summarizes the 24 cases of data. The results showed that in 24 MOF cases, the mortality rate (19/24) was as high as 79.2%. The order of failure organs was lung, kidney, liver, gastrointestinal tract, brain, pancreas, heart and blood system, Age, but not with the GCS score, and that there are some unique features associated with brain disease associated with MOF. Although the current prognosis of MOF is very poor, but timely and correct treatment of each affected organ is the key to the success of treatment.