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目的:阐明2019年位于中缅边境地区的云南省德宏傣族景颇族自治州瑞丽市基孔肯雅热暴发疫情的流行病学特征。方法:开展流行病学调查，收集病例个案调查表，采集患者急性期血清，用PCR-荧光探针法检测基孔肯雅病毒核酸。结果:2019年瑞丽市共确诊基孔肯雅热病例121例，其中本地病例98例(80.99%，包括2例孕妇及其母婴传播的3例新生儿病例即胞胎男婴2例和1例女婴)，缅甸输入性病例23例(19.01%，木姐11例、南坎6例、曼德勒3例、九谷2例、腊戌1例)。疫情主要发生在瑞丽市主城区(勐卯镇)和口岸地区，主要流行期为9～11月份，高峰为10月份(74.38%，90/121)。除母婴传播的3例新生儿病例外，病例年龄最小为3月龄，最大72岁，以20～59岁组为主(77.69%，94/121)。男女性别比为1∶1.28(53：68)。职业分布以商业服务(33.06%)、家务及待业(21.49%)和离退人员(11.57%)居多。结论:2019年瑞丽市发生输入性病例和本地病例并存的基孔肯雅热流行，来自缅甸的输入性病例是引起本地流行的主要原因。此为云南省首次报道本地基孔肯雅热流行，应加强中国—缅甸边境地区基孔肯雅热跨境传播的防控。“,”Objective:To understand the epidemiological characteristics of an outbreak of Chikungunya fever (CHIK) in Ruili city at Sino-Myanmar border area in Yunnan province, China, 2019.Methods:The data of CHIK cases in Ruili city were collected. Serum samples were collected from acute phase of the patients for the detection of the viral nucleic acid with real-time reverse transcription PCR assay.Results:A total of 121 CHIK cases (laboratory-confirmed cases) were reported in Ruili city in 2019, in which 98 were indigenous cases (80.99%) including 2 pregnant women and 3 neonatal cases (twin boys and 1 girl) were observed with vertical mother-to-child transmission), and 23 were imported cases (19.01%) from Myanmar. CHIK mainly occurred in Urban area (Mengmao town) and port area (Jiegao development zone) of Ruili city. The epidemic of CHIK lasted from September to November. The epidemic peak was in October (74.38%). The majority of patients were aged from 20—59 years (77.69%), in addition to 3 cases of mother-to-child transmission, the youngest was 3 months and the oldest 72 year-old. The male to female ratio was 1∶1.28 (53∶68). Occupational distribution of CHIK cases was mainly for the commercial service personnel (33.06%), home workers and unemployed persons (21.49%) and retiree (11.57%).Conclusions:During the outbreak of CHIK in Ruili in 2019, both indigenous and imported cases were detected. The imported CHIK cases from Myanmar were the main sources for local transmission of CHIK in Ruili city. This is the first time that a local epidemic of CHIK has occurred in Yunnan Province. It is necessary to strengthen control of the cross-border spread of CHIK in this area.