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树突状细胞(DC)是目前已知的机体内功能最强的抗原提呈细胞,不仅是机体免疫应答的始动者,而且在诱导免疫耐受、调节T细胞介导的免疫应答方面发挥着重要的作用。近年来,在类风湿关节炎(RA)中的意义逐渐受到重视。文中对DC在RA发病中的作用及药物干预的研究作一综述。
Dendritic cells (DCs) are currently the most potent antigen-presenting cells in the body that act not only as initiators of the immune response in the body but also in inducing immune tolerance and regulating T cell-mediated immune responses Important role. In recent years, the significance of rheumatoid arthritis (RA) has gradually been taken seriously. In this paper, the role of DC in the pathogenesis of RA and the study of drug intervention are reviewed.