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在兔心脏缺血／再灌注（I／R）损伤模型上．对照观察了银杏叶提取物（GBE）的作用。发现：与I／R组相比，I／R＋GBE组血浆中一氧化氛（NO）、超氧化物歧化酶（SOD）、6－酿－前列腺素F1α（6－K－PGF1α）浓度明显升高，而血栓素B2（TXB2）、丙二醛（MDA）明显下降。GBE组血管增多，肿胀内皮细胞减少，线粒体件胀减轻。痉挛球结膜微血管扩张，扩散距离缩小。结果表明：GBE具有明显的扩张微血管作用，尤其对微动脉更明显。这可能由于它能够刺激血管内皮细胞释放NO及PGI2并减少其失活。GBE可被认为是心血管NO释放的刺激剂，用于防治心肌I／R损伤是有效的。
In rabbit heart ischemia / reperfusion (I / R) injury model. The effect of Ginkgo biloba extract (GBE) was observed. Findings: Compared with I/R group, the concentration of NO, SOD, and 6-K-PGF1α in plasma of I/R+GBE group increased significantly. While thromboxane B2 (TXB2) and malondialdehyde (MDA) decreased significantly. In the GBE group, blood vessels increased, swelling of endothelial cells decreased, and mitochondrial swelling eased. The conjunctival microvessels of the RH are expanded and the diffusion distance is reduced. The results showed that: GBE has a significant expansion of microvascular effects, especially for the more obvious arterioles. This may be due to its ability to stimulate vascular endothelial cells to release NO and PGI2 and reduce its inactivation. GBE can be considered as a stimulant of cardiovascular NO release and is effective for preventing myocardial I/R injury.