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目的 为提高未能手术切除晚期胃癌的疗效。方法 采用IORT联合ELF方案加口服Lx(榄香烯 )治疗晚期胃癌 2 2例。结果 PR12例 ,NC 8例 ,PD 2例 ,总有效率 (CR +PR) 54 5% ,生存期最长的 32个月 ,最短的 6个月 ,中位生存期 19 5个月 ;其中 2例达PR后 ,第二次手术切除。IORT未见并发症 ,化疗主要副作用是消化道和骨髓抑制 ,但不严重 ,加上Lx后有协同作用 ,提高了疗效。结论 该综合治疗方法值得进一步研究。
The purpose is to improve the efficacy of unresectable advanced gastric cancer. Methods Twenty two cases of advanced gastric cancer were treated with IORT combined with ELF and oral Lx (elemene). Results PR 12 cases, NC 8 cases, PD 2 cases, the total effective rate (CR + PR) 54 5%, the longest survival period of 32 months, the shortest 6 months, the median survival of 19 5 months; of which 2 Case of PR, the second surgical resection. IORT no complications, the main side effects of chemotherapy is the digestive tract and bone marrow suppression, but not serious, combined with Lx after a synergistic effect to improve the curative effect. Conclusion The comprehensive treatment is worth further study.