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Pharmacyclics公司开发的广谱抗癌药莫特沙芬钆(商品名:Xcytrin()在临床上可单独使用,也可与化疗或放疗联用。其结构为一种具有对称性、高度共轭且富电子的扩展卟啉,能与钆(Ⅲ)紧密结合,分子中的羟丙基和聚乙烯二醇取代基有助于增加水溶性,且所含顺磁离子钆能够被磁共振成像仪(
Pharmacy’s broad-spectrum anticancer drug gadflysdine gadolinium (trade name: Xcytrin (Cl)), which is clinically used alone or in combination with chemotherapy or radiotherapy, has a structure that is symmetrical and highly conjugated The electron-rich extended porphyrin binds closely to gadolinium (III) and the hydroxypropyl and polyethylene glycol substituents in the molecule help to increase water solubility and the gadolinium contained in the paramagnetic gadolinium can be detected by magnetic resonance imaging