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在生理条件下,催乳素和促黄体生成激素共同刺激睾丸固醇类生成。短时催乳素增高,促进睾酮分泌;长期高催乳素血症,则降低睾酮产量并破坏精子生成。男性不育症4%~40%有高催乳素血症。男性高催乳素血症的临床表现有很多变型,如性腺机能减退,性欲降低或消失,阳萎,不育症,男性乳房发育,有5%~10%溢乳。 作者检查男性不育症122例(不包括阻塞性精子缺乏、输精管手术后、隐睾病和临床明显性腺机能不全),其中有25例(20%)催乳素高于正常,年龄20~45岁,平均30.1岁。不育症史1~3年13例,4~6年10例;10年和15年各1例。有流行性腮腺炎病史3例,慢性前列腺炎2例。都没有性腺机能减退
Under physiological conditions, prolactin and luteinizing hormone together stimulate testicular steroidogenesis. Short-term prolactin increased to promote testosterone secretion; long-term hyperprolactinemia, then reduce testosterone production and destroy sperm production. 4% to 40% of male infertility with hyperprolactinemia. There are many clinical manifestations of hyperprolactinemia in men, such as hypogonadism, loss or loss of sexual desire, impotence, infertility, male breast development, with 5% to 10% galactorrhea. The authors examined 122 male infertility (not including obstructive sperm deficiency, vas deferens surgery, cryptorchidism and clinically significant gonadal insufficiency), of which 25 (20%) had higher than normal prolactin, aged 20-45 years , An average of 30.1 years old. Infertility history of 1 to 3 years in 13 cases, 4 to 6 years in 10 cases; 10 years and 15 years in 1 case. A history of mumps in 3 cases, 2 cases of chronic prostatitis. No hypogonadism