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目的探讨原发性输卵管癌的临床表现和诊断方法,以提高临床诊断率。方法回顾性分析本院1996年4月至2004年6月手术治疗的12例原发性输卵管癌患者的临床表现、超声检查、血清CA125水平、病理结果。结果12例患者经病理证实,均为原发性输卵管腺癌。其中仅1例在术前诊断为原发性输卵管癌。12例患者中,4例有阴道流液,4例有阴道不规则流血,4例有腹痛,6例检查发现盆腔包块,超声检查发现盆腔包块有10例。其中彩色多普勒探及肿块内有低阻力的丰富血流9例,合并腹水征1例,术前检查血清CA125 9例高于正常,最高达1184.72 U/m l,宫颈细胞学检查阳性1例。结论原发性输卵管癌临床表现多不典型,不易早期诊断,往往在诊断为其他疾病手术时发现,多已是中晚期。通过分析本组病人的临床资料发现结合超声检查,有助于提高临床对原发性输卵管癌的诊断率。
Objective To investigate the clinical manifestations and diagnosis of primary fallopian tube cancer in order to improve the clinical diagnosis rate. Methods The clinical manifestations, ultrasonography, serum CA125 levels and pathological findings of 12 patients with primary fallopian tube cancer who underwent surgery from April 1996 to June 2004 in our hospital were retrospectively analyzed. Results 12 patients confirmed by pathology, are primary tubal adenocarcinoma. Only 1 of them was diagnosed as primary fallopian tube cancer before surgery. Of the 12 patients, 4 had vaginal fluid, 4 had irregular vaginal bleeding, 4 had abdominal pain, pelvic masses were found in 6 and ultrasound pelvic masses were found in 10 of 10. Color Doppler exploration and mass within the tumor with low resistance in 9 cases of blood flow, 1 case of combined ascites, preoperative serum CA125 9 cases higher than normal, up to 1184.72 U / ml, cervical cytology positive in 1 case . Conclusion The clinical manifestations of primary fallopian tube cancer are atypical, not easy to early diagnosis, often found in the diagnosis of other diseases surgery, mostly in the late. By analyzing the clinical data of patients in this group found that combined with ultrasound, will help to improve the clinical diagnosis of primary fallopian tube cancer.