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目的探讨石蜡油联合戊酸雌二醇片预防宫颈粘连分离术后再粘连的效果。方法收集2012年5月~2014年5月，我院行宫腔粘连分离术患者40例，随机分为观察组与对照组，各20例。对照组术后应用石蜡油，观察组应用石蜡油联合戊酸雌二醇片，比较两组术后再次粘连发生率。结果观察组月经改善率为95.0%，显著高于对照组的80.0%(<0.05)；观察组宫腔再次粘连率为5.0%，显著低于对照组的35.0%(<0.05)。结论石蜡油联合戊酸雌二醇片可有效预防宫颈粘连分离术后再粘连，疗效显著，值得推广应用。“,”Objective To investigate the ef icacy of paraf in oil combined estradiolvalerate in prevention of secondary adhesion after Intrauterine adhesions dissection.Methods 40 patients underwent intrauterine adhesions dissection in our hospital between May 2012 and May 2014 were col ected and randomly divided into observation group and control group, 20 cases in each. The control group received paraf in oil, observation group received paraf in oil combined estradiolvalerate,the incidence of secondary adhesion of the two groups were compared.Results The improvement of menstruation in observation group was 95.0%, significantly higher than the 80.0%in control group ( <0.05);the incidence of secondary adhesion in observation group was 5.0%, significantly lower than the 35.0%in the control group ( <0.05). Conclusion Paraf in oil combined estradiolvalerate for patients with intrauterine adhesions dissection can be ef ective in preventing of secondary adhesion,it has a significant ef ect, should be widely applied.