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CD4+CD25+调节性T细胞(T regulatory cells,Tregs)发挥的免疫负调作用与慢性乙型肝炎发生、发展及预后密切相关,慢性乙型肝炎患者在抗病毒治疗过程中外周血CD4+CD25+Tregs呈现的变化以及发挥的作用备受诸多学者关注,本文就CD4+CD25+Tregs的分类、免疫标志、功能及其与CHB抗病毒的相关研究进行综述.
The immunoregulatory effects of CD4 + CD25 + regulatory T cells (Tregs) are closely related to the occurrence, development and prognosis of chronic hepatitis B. The levels of CD4 + CD25 + The changes of Tregs and the roles they play in this area are of great concern to many scholars. This review summarizes the classification of CD4 + CD25 + Tregs, their immunophenotype, their function and their relationship with CHB antivirus.