论文部分内容阅读
患卵巢癌时发现癌已在腹腔内广泛蔓延者居多,对其治疗应选择做为全身疗法的化学疗法,但过去缺乏对卵巢癌有效的化疗药物,不得不采用属局部疗法范畴的手术及放射疗法。近年强效抗癌药顺氯氨铂(CDDP)的出现,使卵巢癌的化疗与手术均起重要作用。动脉灌注疗法的目的,在于提高病灶局部的药物浓度,减轻副作用,对卵巢癌与盆壁有严重粘连并波及膀胱及结肠病例存在两种意见:一种认为应积极缩小肿瘤体积;另一种认为只须取活组织送病理检查。笔者既往一直赞同前者的见解,也有过严重并发症的体验,因此认为这类病例是动脉灌注疗法的适用对象。实际上,杉木等(1979年)曾报道用5-氟脲嘧啶和环磷酰胺行动脉灌注后再行二次剖腹探查,使根治手术成为可能的病例。立山等报道
Ovarian cancer found in cancer has widespread widespread intraperitoneal, the treatment should choose as a systemic chemotherapy, but in the past the lack of effective chemotherapy for ovarian cancer drugs, had to use the area of local treatment of surgery and radiation therapy. In recent years, the emergence of potent anticancer drug cisplatin (CDDP) plays an important role in the chemotherapy and surgery of ovarian cancer. The purpose of arterial perfusion therapy is to improve the local drug concentration of the lesion, reduce side effects, ovarian cancer and pelvic wall have serious adhesions and affect the bladder and colon cases there are two views: one that should actively reduce the tumor volume; the other that Just take the living tissue sent to pathological examination. The author has always been in favor of the former’s opinion, there have been serious complications of the experience, so that such cases are suitable for arterial infusion therapy. In fact, Cedar et al. (1979) reported that a second laparotomy was performed after arterial infusion of 5-fluorouracil and cyclophosphamide, making radical surgery possible. Tateyama and other reports