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目的探讨硫酸镁与酚妥拉明和硝苯地平联合应用在妊娠高血压综合征患者中的临床效果。方法 80例妊娠高血压综合征患者,随机分为观察组和对照组,各40例。对照组给予酚妥拉明治疗,观察组在对照组基础上给予25%硫酸镁、硝苯地平治疗。比较两组治疗效果。结果对照组显效21例,有效9例,无效10例;观察组显效28例,有效10例,无效2例。观察组总有效率为95.0%(38/40),高于对照组的75.0%(30/40),差异有统计学意义(P<0.05)。结论硫酸镁与酚妥拉明和硝苯地平三药联合在妊娠高血压综合征中的治疗效果显著,具有较好的降压和改善患者临床症状效果,值得借鉴。
Objective To investigate the clinical effect of magnesium sulfate combined with phentolamine and nifedipine in patients with pregnancy induced hypertension. Methods 80 cases of pregnancy induced hypertension syndrome were randomly divided into observation group and control group, 40 cases each. The control group was treated with phentolamine, and the observation group was given 25% magnesium sulfate and nifedipine on the basis of the control group. Compare the treatment effect of two groups. Results In the control group, 21 cases were markedly effective, 9 cases effective and 10 cases ineffective. The observation group was significantly improved in 28 cases, effective in 10 cases and ineffective in 2 cases. The total effective rate in the observation group was 95.0% (38/40), which was higher than that in the control group (75.0%, 30/40). The difference was statistically significant (P <0.05). Conclusion The combination of magnesium sulfate and phentolamine and nifedipine in the treatment of pregnancy-induced hypertension syndrome has significant therapeutic effect, has better antihypertensive effect and improves the clinical symptoms and is worth learning from.