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目的探讨南宁地区孕妇感染TORCH[刚地弓形虫(toxoplasma gondii,TOX)、风疹病毒(rubella virus,RV)、巨细胞病毒(cytomegalovirus,CMV)、单纯性疱疹病毒(herpes simplex virus,HSV)]检出率,做好优生优育并为临床医生提供实验依据。方法对广西壮族自治区妇产医院2014年1~2月2 155例孕妇采用酶联免疫吸附实验(enzyme-linked immunosorbent assay,ELISA)法检测血清中特异性TORCH-IgM进行分析,同时对其中978例进行TORCH-IgG抗体检测,对350例有不良孕产史的孕妇和1 805例正常妊娠孕妇的检测结果进行比较。结果检测发现TORCH-IgM总阳性率为7.61%,其中CMV-IgM、TOX-IgM、RV-IgM、HSV1-IgM、HSV2-IgM阳性率分别为2.01%、1.11%、1.62%、1.48%、1.30%。TOX-IgG、RVIgG、CMV-IgG、HSV1-IgG、HSV2-IgG阳性率分别为4.60%、89.2%、94.9%、87.8%、14.4%。有不良孕产史孕妇血清TORCH-IgM总阳性率为14.57%,高于正常妊娠孕妇(P<0.05)。结论 TORCH感染导致不良妊娠结局,应加强对育龄妇女孕前和孕期TORCH筛查。
Objective To investigate the relationship between TORCH (TOX, TOB), rubella virus (RV), cytomegalovirus (CMV) and herpes simplex virus (HSV) in pregnant women in Nanning. Out rate, good prenatal and postnatal care and clinicians to provide experimental evidence. Methods Serum specific TORCH-IgM was detected by enzyme-linked immunosorbent assay (ELISA) in 2 155 cases of pregnant women in Maternity and Child Hospital of Guangxi Zhuang Autonomous Region from January to February 2014, and 978 cases The TORCH-IgG antibody test was performed to compare the test results of 350 pregnant women with a history of poor pregnancy and 1850 normal pregnant women. Results The positive rate of TORCH-IgM was 7.61%. The positive rates of CMV-IgM, TOX-IgM, RV-IgM, HSV1-IgM and HSV2-IgM were 2.01%, 1.11%, 1.62%, 1.48% %. The positive rates of TOX-IgG, RVIgG, CMV-IgG, HSV1-IgG and HSV2-IgG were 4.60%, 89.2%, 94.9%, 87.8% and 14.4%, respectively. The positive rate of TORCH-IgM in pregnant women with history of adverse pregnancy was 14.57%, higher than that of normal pregnant women (P <0.05). Conclusion TORCH infection leads to adverse pregnancy outcomes. TORCH screening should be strengthened before and during childbearing age.