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目的 :探讨小儿克雷伯杆菌肺炎临床特点及治疗方法。方法 :对2013年1月-2016年1月我院收治的351例小儿肺炎患者的痰液进行菌株鉴定及药敏分析,根据药敏结果针对性的使用抗菌类药物,统计所有患儿的临床治疗有效率。结果 :患儿临床表现为不同程度的发热、咳嗽、喘息、气促等。血常规WBC多正常或轻度升高,以中性粒细胞比例升高为主。X线结果显示,患儿双肺或单肺斑片状阴影、双肺纹理模糊等;痰液培养结果显示,351标本共检测出134株病原菌,以肺炎克雷伯或产酸克雷伯杆菌为主。其中肺炎克雷伯杆菌对哌拉西林/他唑巴坦的敏感性达70.9%;哌拉西林/他唑巴坦治疗结果显示治疗总有效率为97.8%。结论 :哌拉西林/他唑巴坦治疗小儿克雷伯杆菌肺炎疗效较好,可作为首选药物。
Objective: To investigate the clinical characteristics and treatment of Klebsiella pneumonia in children. Methods: From January 2013 to January 2016 in our hospital admitted to 351 cases of children with sputum pneumonia in the identification of strains and drug susceptibility analysis, the use of antimicrobial drugs targeted drug susceptibility results, statistics of all children’s clinical Therapeutic efficiency. Results: Children with clinical manifestations of varying degrees of fever, cough, wheezing, shortness of breath and so on. WBC blood routine or mildly increased, with a high proportion of neutrophils. X ray results showed that children with lung or single lung patchy shadows, blurred lungs and other lungs; sputum culture results showed that 351 specimens were detected in 134 strains of pathogens, Klebsiella pneumoniae or Klebsiella oxytoca Mainly. The susceptibility of Klebsiella pneumoniae to piperacillin / tazobactam was 70.9%. The results of piperacillin / tazobactam treatment showed a total effective rate of 97.8%. Conclusion: Piperacillin / tazobactam is effective in the treatment of Klebsiella pneumonia in children and can be used as the drug of choice.