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近年来,需氧性固紫阴性杆菌引起的感染,尤其是由肠杆菌属和绿脓杆菌引起者,已成为重要课题。这些感染常发生于抗感染力减弱的患者,且有较高的发病率和病死率。此类致病菌对许多抗菌药物有抗药性,如用有效的抗菌素常产生严重的或危及生命的副作用。本文讲述有关的一些抗菌素的选用和抗菌疗法的基本原则,以便对需氧性固紫阴性杆菌引起的感染能进行有效的治疗。表Ⅰ所列的抗菌素,目前认为对这类严重的感染治疗有效。
In recent years, the infection caused by aerobic solid purple negative bacilli, especially those caused by Enterobacter and Pseudomonas aeruginosa, has become an important issue. These infections often occur in patients with reduced anti-infective power, and have a high morbidity and mortality. Such pathogens are resistant to many antimicrobials and often cause serious or life-threatening side effects with effective antibiotics. This article describes the selection of some antibiotics and the basic principles of antimicrobial therapy in order to effectively treat infections caused by aerobic solid purple-negative bacilli. The antibiotics listed in Table I are currently believed to be effective in the treatment of these serious infections.