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胎儿肝脏、骨髓、胸腺细胞混悬液输注治疗22例骨髓增生异常综合征(MDS),包括11例难治性贫血(RA)、4例铁粒幼细胞贫血(RAS)、4例原始细胞增多难治性贫血(RAEB)和3例原始细胞增多难治性贫血转化型(RAEBT)。每例平均接受4.63个胎儿的这种细胞悬液。结果表明,本组病人治疗后第四周血红蛋白和网织红细胞显著增加(P 值分别<0.01;<0.001)。与治疗前比较,血红蛋白、粒细胞和血小板计数在治疗三个月后有效率为54.5%,6月后为50.0%。
Twenty-two patients with myelodysplastic syndrome (MDS) were infused with suspension of fetal liver, bone marrow and thymus cells, including 11 patients with refractory anemia (RA), 4 patients with erythroblastic anemia (RAS), 4 blasts Increased refractory anemia (RAEB) and 3 cases of primitive refractory anaerobic transformation (RAEBT). Each case received an average of 4.63 fetuses of this cell suspension. The results showed that the patients in the fourth week after treatment hemoglobin and reticulocyte significantly increased (P values were <0.01; <0.001). Compared with pre-treatment, hemoglobin, granulocyte and platelet count were 54.5% after three months of treatment and 50.0% after June.