【摘 要】
：
基因芯片表达谱信息,为识别疾病相关基因及对癌症等疾病分型、诊断及病理学研究提供一新途径.在基因表达谱数据中选择特征基因可以提高疾病诊断、分类的准确率,并降低分类器
【机 构】
：
南京航空航天大学自动化学院生物医学工程系
论文部分内容阅读
基因芯片表达谱信息,为识别疾病相关基因及对癌症等疾病分型、诊断及病理学研究提供一新途径.在基因表达谱数据中选择特征基因可以提高疾病诊断、分类的准确率,并降低分类器的复杂度.本文研究了基于离散粒子群(binary particle swarm optimization,BPSO)和支持向量机(support vector machine,SVM)封装模式的BPSO-SVM特征基因选择方法,首先随机产生若干种群(特征子集),然后用BPSO算法优化随机产生的特征基因,并用SVM分类结果指导搜索,最后选出最佳适应度的特征基因子集以训练SVM.结果表明,基于BPSO-SVM的特征基因选择方法,的确是一种行之有效的特征基因选择方法.
其他文献
Heart remodeling is associated with the loss of cardiomyocytes and increase of fibrous tissue owing to abnormal mechanical load in a number of heart disease con
A 3-D chemical transport model (OSLO CTM2) is used to investigate the impact of the increase of NOx emission over China.The model is capable to reproduce basica
Environmental Kuznets characteristics and causes of waste water, waste gas, and solid wastes in Wuhan city was researched; By comparing the variation of "three
The phosphatidylinositol (PI) metabolic pathway is considered critical in plant responses to many environmental factors,and previous studies have indicated the
Influence of packing media on nitrogen removal in a subsurface infiltration system was studied. System A was filled with loamy soil and system B was filled with
This study was undertaken to screen the filamentous fungi isolated from its relevant habitats(wastewater, sewage sludge and sludge cake) for the bioconversion o
Two runs of experiments were carried out to obtain an understanding of phosphorus release and uptake under the anaerobic condition and then the aerobic conditio
目的 研究低嗜中性球发热癌症患者的抗生素给药时间与住院天数、死亡率、转入重症监护室之间的关系.方法 选取2010年1月～2013年12月来新疆医科大学第一附属医院重症医学科就诊
Four environmental and biological monitoring sites were strategically established to evaluate benzene and lead exposure assessment at various traffic zones of B
目的 研究低分子肝素钠治疗急性期非大面积心源性脑栓塞的临床效果并考察患者的病后功能状态.方法 本研究是为期15个月的多中心、随机、对照、单盲试验.入组患者94例被随机分