论文部分内容阅读
目的:探讨我市药品不良反应(ADR)发生的一般情况、特点及影响因素。方法:采用回顾性分类统计,对攀枝花市ADR监测中心2008年收集到的752份ADR报告分别从患者性别、年龄、给药途径、药品分类、累及器官或系统、常见ADR处理措施等方面进行分析、评价。结果:752例ADR中,60岁以上老人所占比例最高,有323例(42.95%);静脉滴注最易导致ADR,有401例(53.32%);涉及810种药品,抗菌药物引起ADR的有317例(39.14%);皮肤及其附件损害最多,有314例(36.38%)。结论:ADR的发生率与患者的年龄、给药途径、临床用药频率等密切相关,临床应予以重视。
Objective: To investigate the general situation, characteristics and influencing factors of adverse drug reaction (ADR) in our city. Methods: Retrospective classification statistics were used to analyze 752 ADR reports collected by ADR surveillance center in 2008 from the aspects of patient’s sex, age, route of administration, drug classification, involved organ or system, and common ADR treatment measures ,Evaluation. Results: Among 752 ADRs, the proportion of elderly over 60 years old was the highest (323 cases, 42.95%). Intravenous infusion most likely resulted in ADR, with 401 cases (53.32%). There were 810 drugs and ADR There are 317 cases (39.14%); the skin and its accessories damage the most, 314 cases (36.38%). Conclusion: The incidence of ADR is closely related to the patient’s age, route of administration, frequency of clinical medication and so on, and should be paid more attention in clinic.