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新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)是指新生儿因围生期缺氧引起的脑部病变,是造成新生儿死亡和儿童脑瘫的主要原因之一。亚低温治疗可以阻止缺氧缺血对大脑组织的进一步损害[1],但仍有40%左右经过亚低温治疗的患儿死亡或遗留严重的神经系统损害。另外急性期的支持治疗和后天康复训练等措施对患儿后期
Hypoxic-ischemic encephalopathy (HIE) is one of the main causes of neonatal death and cerebral palsy in children due to brain damage caused by perinatal hypoxia. Mild hypothermia can prevent further damage to brain tissue caused by hypoxia-ischemia [1], but about 40% of children treated with mild hypothermia still have serious or serious neurological damage. In addition, the acute phase of supportive treatment and acquired rehabilitation measures such as late childhood