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One dinuclear complex [Cu2Cl2(HEMDP) 2]·THF 1(H2EMDP = 2-[(2-hydroxyethylimino)-methyl]-4,6-diiodo-phenol,THF = tetrahydrofuran) has been designed and synthesized by H2EMDP with CuCl2·2H2O in THF solvent. Complex 1 was characterized by UV,IR,ESI-MS,and elemental analyses. 1 was characterized by X-ray crystallography. The crystal belongs to the monoclinic system,space group C2/c with a = 27.886(3) ,b = 8.6890(12) ,c = 26.698(2) ,β = 105.521(2) o,V = 6233.1(12) 3,Z = 8,Mr = 1102.01,μ = 5.533 mm-1,Dc = 2.349 Mg/m3,F(000) = 4112,the final R = 0.0486 and wR = 0.1175(I > 2σ(I)) . In addition,further investigation revealed that the central copper(Ⅱ) atom in the complex is five-coordinated by one nitrogen atom and two oxygen atoms from H2EMDP and two chlorine atoms from chlorid. The 3,5-diiodosalicylaldehyde Schiff base acts as a tridentate ligand. H2EMDP and 1 were assayed for antibacterial(B. subtilis,S. aureus,S. faecalis,P. aeruginosa,E. coli and E. cloacae) activities by MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl trtrazolium bromide) method. 1 showed the most favorable antimicrobial activity with MICs of 3.125,6.25,6.25,12.5,3.125 and 6.25 μg/mL against B. subtilis,S. aureus,S. faecalis,P. aeruginosa,E. coli and E.cloacae,respectively.
One dinuclear complex [Cu2Cl2 (HEMDP) 2] THF 1 (H2EMDP = 2 - [(2-hydroxyethylimino) -methyl] -4,6-diiodo-phenol, THF = tetrahydrofuran) has been designed and synthesized by H2EMDP with CuCl2 2H2O in THF solvent. Complex 1 was characterized by UV, IR, ESI-MS, and elemental analyzes. 1 was characterized by X-ray crystallography. The crystal belongs to the monoclinic system, space group C2 / c with a = 27.886 , b = 8.6890 (12), c = 26.698 (2) β, β = 105.521 (2) o, V = 6233.1 (12) 3, Z = 8, Mr = 1102.01, μ = 5.533 mm-1, = 2.349 Mg / m3, F (000) = 4112, the final R = 0.0486 and wR = 0.1175 (I> 2σ (I)). In addition, further investigation revealed that the central copper (II) atom in the complex is five -coordinated by one nitrogen atom and two oxygen atoms from H2EMDP and two chlorine atoms from chlorid. The 3,5-diiodosalicylaldehyde Schiff base acts as a tridentate ligand. H2EMDP and 1 were assayed for antibacterial (B. subtilis, S. aureus, S faecalis, P. aeruginosa, E. coli and E. cloacae) activities by MTT ( 3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyl trtrazolium bromide). 1 showed the most favorable antimicrobial activity with MICs of 3.125, 6.25, 6.25, 12.5, 3.125 and 6.25 μg / mL against B . subtilis, S. aureus, S. faecalis, P. aeruginosa, E. coli and E. cloacae, respectively.