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[目的 ]了解汕头市健康人群麻疹、百日咳、白喉的免疫状况 ,评价计免 -冷链工作质量 ,为免疫策略提供依据。[方法 ] 2 0 0 3年对汕头市龙湖区和濠江区等两个区 180名健康者进行麻疹、白喉和百日咳抗体水平监测。在 2～ 4岁、6～ 8岁和 13～ 15岁年龄组各随机抽取 60名监测对象 ,用ELISE法检测麻疹抗体水平 ,凝集试验检测百日咳抗体水平 ,间接血凝试验检测白喉抗体水平。[结果 ] 180个监测对象的麻疹、白喉和百日咳全程免疫史达 90 %以上。 3个年龄组的麻疹、白喉的抗体保护率均达 10 0 % ,百日咳的抗体阳性率在 78 3 %～ 98 3 % ,保护率仅为 2 8 3 %～ 43 3 %。[结论 ]汕头市已建立对麻疹、百日咳和白喉较高的免疫屏障 ,免疫成功率亦较满意
[Objective] To understand the immune status of measles, whooping cough and diphtheria in healthy population in Shantou and to evaluate the quality of free-cold chain work and provide the basis for immunization strategy. [Methods] In 2003, the levels of measles, diphtheria and pertussis antibodies in 180 healthy subjects in Longhu District and Haojiang District of Shantou City were monitored. Sixty-two subjects were randomly selected from 2 to 4 years old, 6 to 8 years old and 13 to 15 years old group. ELISAs were used to detect measles antibody levels, agglutination test to detect the level of pertussis antibody and indirect hemagglutination test to detect diphtheria antibody level. [Results] The measles, diphtheria and pertussis immunization history of 180 subjects were over 90%. Antibody protection rates of measles and diphtheria in all three age groups were up to 100%. The antibody positive rate of pertussis was 78.3% ~ 98.3% and the protection rate was only 28.3% ~ 43.3%. [Conclusion] Shantou has established a higher immune barrier against measles, whooping cough and diphtheria, and the immunization success rate is also satisfactory