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目的:研究急性有机磷中毒(AOPP)致循环衰竭患者的血流动力学变化。方法:总结26例AOPP致循环衰竭患者48h内的血流动力学变化,并分析生存者与死亡者的差别。结果:与正常参考均值比较:SVI、LVSWI在48h内显著降低(P<0.01);RVSWI在24h内显著降低(P<0.01);CI在16h内显著降低(P<0.01)。与同组2h比较,生存者的CI、SVI、LVSWI/RVSWI在24h后明显改善(P<0.05或P<0.01),血乳酸显著降低(P<0.05或P<0.01);死亡者无改善。结论:AOPP致循环衰竭患者的心脏做功能力明显受损,治疗后生存者状况可以改善。
Objective: To study the hemodynamic changes in patients with circulatory failure caused by acute organophosphate poisoning (AOPP). Methods: The hemodynamic changes in 26 patients with circulatory failure caused by AOPP within 48 hours were summarized, and the difference between survivors and those who died was analyzed. Results: Compared with the normal reference value, the SVI and LVSWI decreased significantly within 48 hours (P <0.01); RVSWI decreased significantly within 24 hours (P <0.01); CI significantly decreased within 16 hours (P <0.01). Compared with the same group 2h, CI, SVI, LVSWI / RVSWI in survivors were significantly improved after 24h (P <0.05 or P <0.01), blood lactate was significantly decreased (P <0.05 or P <0.01); CONCLUSIONS: The cardiac function of patients with AOPP-induced circulatory failure is significantly impaired and the condition of survivors after treatment is improved.