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目的探讨检测血清降钙素原(PCT)在婴幼儿腹泻时的临床意义,为婴幼儿腹泻的病因诊断、治疗提供理论依据。方法对我院146例婴幼儿腹泻分为细菌感染组33例和轮状病毒感染组46例和非感染组67例(包括生理性腹泻,如母乳的营养成分超过小儿的生理需要量和消化功能的限度时;喂食不当可引起腹泻,如喂养不定时、量过多或过少或食物成分不适宜等)三组,检测血清PCT进行回顾性分析分析。结果当PCT≥0.1ng/ml时,细菌感染组与轮状病毒感染组相比有显著的统计学意义(χ2=40.1,P<0.05),细菌感染组与非感染组相比有显著的统计学意义(χ2=47.5,P<0.05)。结论细菌感染时血清PCT早期即升高,可作为婴幼儿腹泻病因诊断及治疗有价值的早期指标。
Objective To investigate the clinical significance of detecting serum procalcitonin (PCT) in infants with diarrhea and provide a theoretical basis for the diagnosis and treatment of infantile diarrhea. Methods 146 cases of infantile diarrhea in our hospital were divided into bacterial infection group 33 cases and rotavirus infection group 46 cases and 67 cases of non-infected group (including physiological diarrhea, such as breast milk nutrients than children’s physiological needs and digestive function Of the time; improper feeding can cause diarrhea, such as feeding from time to time, too much or too little or inappropriate food composition, etc.) three groups, detection of serum PCT for retrospective analysis. Results When PCT≥0.1 ng / ml, there was a significant difference between the bacterial infection group and the rotavirus infection group (χ2 = 40.1, P <0.05). There was significant statistical difference between the bacterial infection group and the non-infected group Significance (χ2 = 47.5, P <0.05). Conclusions Serum PCT is elevated early in bacterial infection and may be used as an early indicator of the etiological diagnosis and treatment of infantile diarrhea.