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脑膜炎双球菌感染的主要特点是鼻咽带菌者多,是与多种因素有关。近几年有关流脑免疫学的研究,国内外均有报道,一般认为脑膜炎双球菌侵入人体后,主要产生体液性免疫,并在呼吸道可刺激诱生局部分泌型IgA(SIgA)。但对于流脑带菌者的免疫功能,国内则尚未见报道。本文拟从这一方面进行探讨,为防治流脑提供科学依据。于1981年3～4月对中小学生的112例流脑带菌者和104例健康者进行了植物血球凝集素(PHA)皮肤试验及血清中IgA、IgG、IgM和唾液中SIgA测定。
The main feature of meningococcal infection is that there are many nasopharyngeal infections, which are related to many factors. In recent years, researches on the immunology of meningitis have been reported both at home and abroad. It is generally believed that meningococcus inoculation mainly produces humoral immunity and stimulates the production of local secreted IgA (SIgA) in the respiratory tract. However, the immune function of meningococcal carriers in China has not yet been reported. This article intends to explore from this aspect, to provide a scientific basis for the prevention and control of meningitis. From March to April 1981, 112 cases of meningococcal carriers and 104 healthy volunteers were enrolled in the skin test of hemagglutinin (PHA) and the serum IgA, IgG, IgM and SIgA in saliva.