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在一项新的研究中,来自美国威尔康奈尔医学院的研究人员发现干细胞在细胞分裂后利用它们的基因上的一系列蛋白“标签”保持它们的身份。这一结果可能有助进一步理解癌症等某些疾病如何产生,并且可能在抵抗疾病中发挥着广泛的临床影响。相关研究结果发表在Cell Reports期刊上。多能性干细胞(PSC)能够转化为体内的任何一种类型的细胞。每个干细胞变成何种类型的细胞是由多种蛋白调节的一种受到严格控制的系统决定着的。当每个干细胞进行有丝分裂时,所产生的每个所谓的子细胞应当与它的起源细胞具有相同的细胞类型。但是在有丝分裂期间,这种
In a new study, researchers from Weill Cornell Medical School in the United States found that stem cells retain their identity with a range of proteins on their genes after cell division. This result may help to further understand how certain diseases such as cancer develop and may have a broad clinical impact in disease resistance. Relevant research results published in the Cell Reports journals. Pluripotent stem cells (PSCs) can be transformed into any type of cell in the body. What type of cells each stem cell becomes is determined by a tightly controlled system that is regulated by a variety of proteins. When each stem cell is mitotic, each so-called daughter cell produced should have the same cell type as its origin cell. But during mitosis, this